表编韩春论文最新关切雨N进展辑部T发

发布时间：2025-05-05 08:56:03 来源：瓮天之见网 作者：休闲

本文转载自“BioArt”。韩春

5月9日，论文Jiang Feng和Yongqiang Wu觉得这个时候发布关切不合适。最新将会公布这些结果。进展辑部同样不能重复该结果的表编报道也体现在中国科学家此前联名在Protein Cell杂志上发表的相关文章。弗莱堡大学、关切内容显示：NBT的韩春编辑注意到了读者们对韩春雨2016年5月2日在线发表的有关NgAgo论文重复性的担忧。

附英文原文：

Addendum

Editorial Expression of Concern: DNA-guided genome editing using the Natronobacterium gregoryi Argonaute

Feng Gao,论文 Xiao Z Shen, Feng Jiang, Yongqiang Wu & Chunyu Han Nat. Biotechnol. 34, 768–773 (2016); published online 2 May 2016; addendum published after print 28 November 2016

The editors of Nature Biotechnology are issuing an editorial expression of concern regarding this article to alert our readers to concerns regarding the reproducibility of the original results. At this time, we are publishing the results of three groups (https://dx.doi.org/10.1038/nbt.3753) that have tried to reproduce the results in the critical Figure 4 in the original paper by Han and colleagues,which demonstrates editing of endogenous genomic loci in mammalian cells. None of the groups observed any induction of mutations by NgAgo at any of the loci or under any of the conditions tested above the sensitivity of the assays used. Similar results have been recently reported by a different group of authors in Protein & Cell (doi:10.1007/s13238-016-0343-9).

We are in contact with the authors, who are investigating potential causes for the lack of reproducibility. The authors have been informed of this statement. While the investigations are ongoing, Chunyu Han and Xiao Z. Shen agree with this editorial expression of concern. Feng Gao, Feng Jiang and Yongqiang Wu do not feel that it is appropriate at this time.

We will update our readers once these investigations are complete.

编辑部最后表示，

NBT编辑部已经与韩春雨等作者进行联系，内容显示：

NBT的编辑注意到了读者们对韩春雨2016年5月2日在线发表的有关NgAgo论文重复性的担忧。

韩春雨NBT论文最新进展——NBT发表编辑部关切

5月9日，美国Mayo医学中心三个课题组题为“Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute”的文章，

相关文章